By David E. Schteingart (auth.), Gary D. Hammer, Tobias Else (eds.)
This first version of the textbook “Adrenocortical Carcinoma: uncomplicated Sciences and scientific suggestions” presents a concise compilation of correct information advancing our present realizing of this infrequent melanoma. Chapters are devoted to a variety of points of either the elemental biology and the scientific technological know-how on the subject of adrenocortical carcinoma (ACC). specialist clinicians introduce the reader to present state of the art medical care of sufferers with ACC. As a substantial physique of data on ACC has accrued over the past many years, professional scientists have authored extra sections that function a reference resource for the skilled researcher in addition to an creation for the trainee within the laboratory or sanatorium. scientific subject matters span the epidemiology, prognosis and remedy of ACC. clinical subject matters parts span the pathology and pathophysiology of ACC with a different specialise in experimental versions of adrenocortical tumors and up to date advances within the genetic points and signaling pathways in ACC. The content material of this ebook was once compiled and edited with the motive of facilitating the interpretation of data into destiny diagnostic and healing instruments that may finally increase sufferer care.
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In case of a high suspicion of an ACC, needle biopsy is contraindicated pre-operatively; spillage of tumor cells will prevent cure (Fig. 1a, b). 3. Incisions allowing wide local exposure of the tumor and intra-abdominal metastases, making every effort to avoid rupturing the tumor capsule when it is localized and potentially curable. 4. Avoidance of laparoscopic techniques. 5. Preparation for possible aortopulmonary bypass in cases where tumor extends into the vena cava. This assumes appropriate pre-operative imaging in all patients (Fig.
N Engl J Med 322(17):1195–1201 26. Falchuk KR (1973) Inappropriate antidiuretic hormone-like syndrome associated with an adrenocortical carcinoma. Am J Med Sci 266(5):393–395 27. Yamanaka K et al (2000) A case of renin-producing adrenocortical cancer. Endocr J 47(2):119–125 28. Oka T et al (1996) Erythropoietin-producing adrenocortical carcinoma. Urol Int 56(4): 246–249 29. Fragoso MC et al (2007) An inhibin B and estrogen-secreting adrenocortical carcinoma leading to selective FSH suppression.
Michalkiewicz E et al (2004) Clinical and outcome characteristics of children with adrenocortical tumors: a report from the International Pediatric Adrenocortical Tumor Registry. J Clin Oncol 22(5):838–845 11. Pianovski MA et al (2006) Mortality rate of adrenocortical tumors in children under 15 years of age in Curitiba, Brazil. Pediatr Blood Cancer 47(1):56–60 12. Ribeiro RC et al (2001) An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma.
Adrenocortical Carcinoma: Basic Science and Clinical Concepts by David E. Schteingart (auth.), Gary D. Hammer, Tobias Else (eds.)