By Joshua Mitteldorf
Because the Nineties, laboratory characterization of getting older has been diverging from predictions of evolutionary thought, specifically within the zone of genetics. at the same time, a technology of multilevel choice has discovered its position within the evolutionary literature. the writer means that facts warrants attention of a brand new paradigm for evolution of getting older, and proposes the demographic conception of senescence, wherein getting older has been affirmatively chosen since it degrees the loss of life fee through the years, aiding to stabilize inhabitants dynamics and stop extinctions. Read more...
summary: because the Nineties, laboratory characterization of getting older has been diverging from predictions of evolutionary conception, specially within the region of genetics. at the same time, a technological know-how of multilevel choice has came upon its position within the evolutionary literature. the writer means that proof warrants attention of a brand new paradigm for evolution of getting older, and proposes the demographic conception of senescence, wherein getting older has been affirmatively chosen since it degrees the demise expense through the years, assisting to stabilize inhabitants dynamics and forestall extinctions
Read or Download Aging is a group-selected adaptation: theory, evidence, and medical implications PDF
Similar geriatrics books
"I welcome with enthusiasm the 3rd version of this booklet for households and neighbors of sufferers with dementing health problems. It has served good in its previous appearances and will accomplish much more with this version. " -- Paul R. McHugh, M. D. , within the forewordThrough versions, this best-selling e-book has remained the "bible" for households who're giving care to individuals with Alzheimer illness.
Offers optimistic and sensible support for all these interested by aged care. This publication is a necessary instruction manual to extend wisdom.
Perspektiven für Gestalter! Wenn wir davon ausgehen müssen, dass die wachsenden Anforderungen an Leitende Ärzte und die Arbeitsverdichtung erst den Beginn eines Zyklus markieren und keineswegs sein Ende, wird deutlich, dass es Werkzeuge und Techniken braucht, um die verantwortungsvolle place auch in Zukunft erfolgreich gestalten zu können.
This groundbreaking source provides a wealth of findings and views formerly unseen within the LGBT literature. Its specialize in mental, sociopolitical and care supply concerns affecting LGBT elders finds either the nuanced interaction among varied resources of identification and a number of resources of stigma and discrimination.
Extra resources for Aging is a group-selected adaptation: theory, evidence, and medical implications
Sometimes the former is referred to as “squaring the mortality curve” and we can see why in the example below, which is a qualitative representation, valid for no animal in particular. Hormesis 7 “Squaring the Mortality Curve” Number remaining alive Preventing premature deaths Age Number remaining alive Delayed Aging Both mean and maximum lifespan Age Survival curves: Red is extended by intervention, blue without. Top: Early mortality is reduced, but late life mortality is increased so that the two curves converge at late ages.
298(5594): p. 830-4. 57. Hsin, H. and C. Kenyon, Signals from the reproductive system regulate the life span of C. elegans. Nature, 1999. 399(6734): p. 362-366. 58. , The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J. , 1986. 116(4): p. 641-54. 59. , Dietary modulation of reproductive function, In: Modulation of Aging Processes by Dietary Restriction, B. Yu, Editor. 1994, CRC Press: Cleveland, OH. p. 221-246. 60. , Effects of exercise and dietary restriction on energy metabolism and longevity, In: Modulation of Aging Processes by Dietary Restriction, B.
Exp. , 2007. 42(8): p. 709-712. 20. , Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature, 2012. 21. , Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys. Nature communications, 2014. 5. 22. , Demography of dietary restriction and death in Drosophila. Science, 2003. 301(5640): p. 1731-1733. 23. P. B. Kirkwood, Calorie restriction and aging: a life-history analysis. Evolution Int. J. Org. Evolution, 2000. 54(3): p. 740-50.
Aging is a group-selected adaptation: theory, evidence, and medical implications by Joshua Mitteldorf